what is the unit to unit conversion of humalog to novolo
- ACRONYMS AND DEFINITIONS
- Elapsing of action - time flow from first measurable effect until last measurable effect
- Onset of action - time period from injection until first measurable effect
- Peak effect - time flow from injection until greatest result
- RAPID Acting INSULINS
Admelog® (insulin lispro)
Dosage forms
SoloStar® Pen (100 units/ml)
- 3 ml pen
- Comes in carton of 5 pens
- Compatible with BD Ultra-Fine®, Ypsomed Clickfine®, and Owen Mumford Unifine® needles
Vial (100 units/ml)
- Comes in three ml and ten ml vials
Pharmacokinetics
Onset of activeness
- x - 30 minutes
Duration of action
- 3 - 5 hours
Peak effect
- 1/two - 2 hours
Mixing
- Exercise NOT MIX with other insulins
Dosing
- Dosage will vary by patient
- Admelog® is a premeal (prandial) insulin. See insulin dosing for more.
- Inject Admelog® inside 15 minutes before a repast or immediately after a repast
Other
- Admelog® should exist clear and colorless
- Admelog® is compatible with some insulin pumps
Storage
Unpunctured, refrigerated
- Vials and pens are good until expiration appointment on product
Unpunctured, room temp
- Vials and pens are good for 28 days
Punctured (in use)
- Pens should be kept at room temperature (do non refrigerate)
- Vials may be refrigerated or kept at room temp
- Vials and pens are good for 28 days
Afrezza® (inhaled insulin)
Dosage forms
Cartridge
- iv unit cartridge of inhalation pulverization
- 8 unit of measurement cartridge of inhalation pulverization
Packaged as follows:
- lx four unit cartridges
- 90 four unit cartridges
- 90 eight unit cartridges
- 60 four unit and 30 8 unit
- 30 four unit and lx eight unit
- 90 four unit and ninety eight unit
Pharmacokinetics
Onset of action
- 10 - xxx minutes
Duration of action
- ∼ 2.half-dozen hours
Dosing
Insulin-naïve patients
- 4 units with the first of each meal
Other
- Run into Inhaled insulin for a consummate review of Afrezza®
Storage
Packaging
- Afrezza® comes in a sealed foil bundle with 2 blister cards inside
- Each blister card has 5 rows of 3 cartridges
- three cartridges are nether 1 cicatrice
- Before use, cartridge and inhaler should be at room temperature for 10 minutes
- Inhaler should exist thrown abroad later 15 days
Refrigerated
- Sealed foil packet is practiced until expiration engagement
Room temperature
- Sealed foil package - employ inside 10 days
- Sealed blister cards + strips - use inside 10 days
- Opened blister - use within iii days
Apidra® (insulin glulisine)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
SoloStar® Pen (100 units/ml)
- iii ml pen
- Comes in package of 5 pens
- Compatible with all BD® pen needles
Pharmacokinetics
Onset of action
- 10 - 30 minutes
Duration of activeness
- iii - v hours
Peak outcome
- i/2 - 2 hours
Mixing
- Mix with NPH only
- Describe Apidra® first, so NPH
- Inject immediately
Dosing
- Dosage volition vary by patient
- Apidra® is a premeal (too called prandial) insulin. See insulin dosing for more.
- Inject Apidra® inside 15 minutes before a meal or within 20 minutes later starting a meal
Other
- Apidra® should be clear and colorless
- Apidra® is compatible with some insulin pumps
Storage
Unpunctured, refrigerated
- Vials and pens are good until expiration date on product
Unpunctured, room temp
- Vials and pens are proficient for 28 days
Punctured (in utilize)
- Pens should be kept at room temperature (exercise non air-condition)
- Vials may be refrigerated or kept at room temperature
- Vials and pens are good for 28 days
Fiasp® (insulin aspart)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
FlexTouch Pen® (100 units/ml)
- 3 ml pen
- Comes in carton of 5 pens
- Uniform with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of activeness
- 15 - 20 minutes
Duration of action
- 5 - seven hours
Peak effect
- 90 - 133 minutes
Mixing
- Practise NOT MIX with other insulins
Dosing
- Dosage will vary by patient
- Fiasp® is a premeal (prandial) insulin. See insulin dosing for more than.
- Inject Fiasp® at the first of a meal or within 20 minutes subsequently starting a meal
- Fiasp® is approved for use in some insulin pumps
Other
- Fiasp® should be clear and colorless
- Fiasp® is canonical for apply in some insulin pumps
Storage
Unpunctured, refrigerated
- Vials and pens are practiced until expiration date on product
Unpunctured, room temp
- Vials and pens are good for 28 days
Punctured
- Vials and pens may be refrigerated or kept at room temperature
- Vials and pens are proficient for 28 days
Humalog® (insulin lispro)
Dosage forms
| Humalog products | ||||
|---|---|---|---|---|
| Proper name | Volume | Concentration | Max dose per injection | Package size |
| U-100 vial | 3 ml and 10 ml | 100 units/ml | Northward/A | 1 vial |
| U-100 cartridge * | 3 ml | 100 units/ml | N/A | 5 cartridges |
| U-100 KwikPen | iii ml | 100 units/ml | 60 units | five pens |
| U-100 Tempo Pen ‡ | 3 ml | 100 units/ml | 60 units | 5 pens |
| U-100 Junior KwikPen ✝ | 3 ml | 100 units/ml | 30 units | 5 pens |
| U-200 KwikPen | three ml | 200 units/ml | 60 units | two pens |
Needles
- KwikPen® is compatible with all BD® pen needles
Pharmacokinetics
Onset of action
- 10 - 30 minutes
Elapsing of action
- iii - 5 hours
Peak outcome
- 1/2 - 2 hours
Mixing
- Mix with NPH only
- Draw Humalog® first, then NPH
- Inject immediately
Dosing
- Dosage volition vary by patient
- Humalog® is a premeal (prandial) insulin. See insulin dosing for more than.
- Inject Humalog® within 15 minutes earlier a meal or immediately after a meal
Other
- Humalog® should be clear and colorless
- Humalog® is compatible with some insulin pumps
- HumaPen® Luxura HD is a reusable pen that allows dosing in 0.5 unit increments
- HumaPen® Memoir records the fourth dimension, date, and dose of the last 16 injections
Storage
Unpunctured, refrigerated
- Vials, pens, and cartridges are good until expiration date on product
Unpunctured, room temp
- Vials, pens, and cartridges are good for 28 days
Punctured (in use)
- Vials may exist refrigerated or kept at room temperature
- Pens and cartridges should be kept at room temperature (practice not air-condition)
- Vials, pens, and cartridges are good for 28 days
Lyumjev® (insulin lispro-aabc)
Dosage forms
| Lyumjev products | ||||
|---|---|---|---|---|
| Proper name | Volume | Concentration | Max dose per injection | Package size |
| U-100 vial | 10 ml | 100 units/ml | N/A | 1 vial |
| U-100 cartridge * | 3 ml | 100 units/ml | N/A | v cartridges |
| U-100 KwikPen | 3 ml | 100 units/ml | 60 units | 5 pens |
| U-100 Junior KwikPen ✝ | 3 ml | 100 units/ml | 30 units | 5 pens |
| U-100 Tempo Pen ‡ | 3 ml | 100 units/ml | 60 units | 5 pens |
| U-200 KwikPen | three ml | 200 units/ml | 60 units | 2 pens |
Pharmacokinetics
Onset of action
- fifteen - xx minutes
Elapsing of action
- 4 - 8 hours
Mixing
- Do NOT MIX with other insulins
Dosing
- Dosage will vary by patient
- Lyumjev® is a premeal (prandial) insulin. See insulin dosing for more.
- Inject Lyumjev® at the start of a meal or within 20 minutes subsequently starting a meal
Other
- Lyumjev® should be articulate and colorless
Storage
Unpunctured, refrigerated
- Vials, pens, and cartridges are practiced until expiration date on product
Unpunctured, room temp
- Vials, pens, and cartridges are good for 28 days
Punctured (in use)
- Vials may be refrigerated or kept at room temperature
- Pens and cartridges should be kept at room temperature (exercise not air-condition)
- Vials, pens, and cartridges are proficient for 28 days
Novolog® (insulin aspart)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
FlexPen® (100 units/ml)
- 3 ml pen
- Comes in package of 5
- Compatible with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
FlexTouch® Pen (100 units/ml)
- three ml pen
- Comes in package of 5
- FlexTouch® pen button maintains the same extension at all doses
- Compatible with NovoFine® and NovoTwist® pen needles
Cartridge (100 units/ml)
- 3 ml cartridge
- for use in NovoPen® reusable pens
Pharmacokinetics
Onset of action
- 10 - 30 minutes
Duration of action
- 3 - 5 hours
Mixing
- Mix with NPH only
- Draw Novolog® first, then NPH
- Inject immediately
Dosing
- Dosage will vary by patient
- Novolog® is a premeal (also called prandial) insulin. Meet insulin dosing for more than.
- Inject Novolog® within v - 10 minutes before a meal
Other
- Novolog® should be clear and colorless
- Novolog® is compatible with some insulin pumps
Storage
Unpunctured, refrigerated
- Vials, pens, and cartridges are practiced until expiration date on product
Unpunctured, room temp
- Vials, pens, and cartridges are expert for 28 days
Punctured (in use)
- Vials may be refrigerated or kept at room temperature
- Pens and cartridges should be kept at room temperature (practice not air-condition)
- Vials, pens, and cartridges are expert for 28 days
- SHORT ACTING INSULINS
Humulin® R (regular insulin)
Dosage forms
Humulin® R U-100 Vial
- Contains 100 units/ml
- Comes in iii ml and ten ml vials
Humulin® R U-500 Vial
- Contains 500 units/ml
- 20 ml vial
- A special U-500 syringe must be prescribed with vial
Humulin® R U-500 KwikPen®
- Contains 500 units/ml
- iii ml pen
- Comes in carton of two or 5 pens
- BD® pen needles are recommended
Pharmacokinetics
Onset of action
- 30 - hr
Duration of action
- six - viii hours
Mixing
- Mix with NPH only
- Draw Humulin® R offset, then NPH
- Inject immediately
Dosing
- Dosage will vary by patient
- Humulin® R is a premeal (also chosen prandial) insulin. See insulin dosing for more than.
- Humulin® R should be followed by a meal inside approximately xxx minutes of administration
Other
- Humulin® R should be clear and colorless
- Humulin® R U-500 should just be prescribed to patients who require > 200 units of insulin per day
Storage U-100
Unpunctured, refrigerated
- Vials are good until expiration date on product
Unpunctured, room temp
- Vials are good for 31 days
Punctured (in utilize)
- Vials may be refrigerated or kept at room temperature
- Vials are proficient for 31 days
Storage U-500
Unpunctured, refrigerated
- Vials and pens are good until expiration engagement on product
Unpunctured, room temp
- Vials are adept for xl days
- Pens are expert for 28 days
Punctured (in utilize)
- Pens should exist kept at room temperature (do not refrigerate)
- Vials may be refrigerated or kept at room temperature
- Pens are skilful for 28 days
- Vials are good for twoscore days
Novolin® R (regular insulin)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
Flexpen (100 units/ml)
- 3 ml pen
- Comes in carton of 5 pens
- Compatible with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of activity
- thirty - threescore minutes
Duration of action
- 6 - 8 hours
Mixing
- Mix with NPH only
- Draw Novolin® R starting time, then NPH
- Inject immediately
Dosing
- Dosage will vary by patient
- Novolin® R is a premeal (too called prandial) insulin. Encounter insulin dosing for more.
- Novolin® R should generally be injected approximately thirty minutes prior to the start of a repast
Other
- Novolin® R should be clear and colorless
Storage
Unpunctured, refrigerated
- Vials and pens are good until expiration date on product
Unpunctured, room temp
- Vials are good for 42 days
- Pens are practiced for 28 days
Punctured (in utilize)
- Vials and pens should exist kept at room temperature (do not refrigerate)
- Vials are good for 42 days
- Pens are good for 28 days
- INTERMEDIATE Interim INSULINS
Humulin® N | NPH | Human insulin isophane suspension
Dosage forms
Vial (100 units/ml)
- Comes in 3 ml and 10 ml vials
KwikPen® (100 units/ml)
- 3 ml pen
- Comes in packet of 5
- Compatible with BD® pen needles
Pharmacokinetics
Onset of action
- 2 - 4 hours
Duration of action
- up to 20 hours
Mixing
- Humulin® N can be mixed with Regular, Apidra®, Humalog®, and Novolog®
- Draw Humulin® N afterward other insulin
- Inject immediately
Dosing
- Run into NPH dosing for recommendations on dosing NPH insulin
- See converting between insulin brands and types for data on changing insulins
Other
- Humulin® Due north should be mixed before utilize (see instructions with product)
- Humulin® N should appear uniformly cloudy with no particulate matter after mixing
Storage
Unpunctured, refrigerated
- Vials and pens are good until expiration date on product
Unpunctured, room temp
- Vials are proficient for 31 days
- Pens are proficient for 14 days
Punctured (in apply)
- Vials may be refrigerated or kept at room temp
- Pens should be kept at room temperature (do not refrigerate)
- Vials are good for 31 days
- Pens are proficient for 14 days
Novolin® N | NPH | Isophane insulin human suspension
Dosage forms
Vial (100 units/ml)
- 10 ml vial
FlexPen (100 units/ml)
- three ml pen
- Comes in carton with five pens
- Uniform with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of action
- 2 - 4 hours
Duration of action
- upward to 20 hours
Mixing
- Novolin® Due north can be mixed with Regular, Apidra®, Humalog®, and Novolog®
- Draw Novolin® N afterward other insulin
- Inject immediately
Dosing
- See NPH dosing for recommendations on dosing NPH insulin
- See converting betwixt insulin brands and types for data on changing insulins
Other
- Novolin® Due north should exist mixed before use (see instructions with production)
- Novolin® Northward should appear uniformly cloudy with no particulate thing subsequently mixing
Storage
Unpunctured, refrigerated
- Vials and pens are skilful until expiration appointment on product
Unpunctured, room temp
- Vials are good for 42 days
- Pens are skilful for 28 days
Punctured (in apply)
- Vial and pens should be stored at room temperature (do not refrigerate)
- Vials are skillful for 42 days
- Pens are expert for 28 days
- LONG Interim INSULINS
Basaglar® (insulin glargine)
Dosage forms
Kwikpen (100 units/ml)
- 3 ml pen
- Comes in package of 5 pens
- Compatible with BD® pen needles
Tempo Pen (100 units/ml)
- 3 ml pen
- Comes in package of v pens
- Compatible with BD® pen needles
- Tempo pen connects to a phone app and relays dosing information
Pharmacokinetics
Onset of activeness
- 1 - three hours
Duration of action
- 24+ hours
Mixing
- DO Not MIX with other insulins
Dosing
- Dosage will vary past patient
- The recommended starting dose of Basaglar® in patients with type 2 diabetes who are not currently treated with insulin is 10 units (or 0.2 units/kg) once daily
- Basaglar® may be administered at any fourth dimension during the day
- Basaglar® should exist administered at the same fourth dimension every day
- Basaglar® is a basal insulin. Come across insulin dosing for more.
- Meet converting betwixt insulin brands and types for data on changing insulins
Other
- Basaglar® should be clear and colorless
Storage
Unpunctured, refrigerated
- Pens are good until expiration date on product
Unpunctured, room temp
- Pens are good for 28 days
Punctured (in use)
- Pens should be kept at room temperature (practise not refrigerate)
- Pens are good for 28 days
Lantus® (insulin glargine)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
SoloStar® Pen (100 units/ml)
- three ml pen
- Comes in package of 5 pens
- Compatible with BD® pen needles
Pharmacokinetics
Onset of action
- ane - 3 hours
Elapsing of activity
- 24+ hours
Mixing
- Do NOT MIX with other insulins
Dosing
- Dosage will vary by patient
- The recommended starting dose of Lantus® in patients with blazon 2 diabetes who are non currently treated with insulin is 0.ii units/kg or up to 10 units once daily
- Lantus® may be administered at whatever fourth dimension during the day
- Lantus® should exist administered at the same fourth dimension every day
- Lantus® is a basal insulin. See insulin dosing for more than.
- See converting between insulin brands and types for information on irresolute insulins
Other
- Lantus should be clear and colorless
- Semglee is a biosimilar to Lantus and can be substituted for it
Storage
Unpunctured, refrigerated
- Vials and pens are adept until expiration date on product
Unpunctured, room temp
- Vials and pens are proficient for 28 days
Punctured (in use)
- Vials may be refrigerated or kept at room temperature
- Pens should exist kept at room temperature (do not refrigerate)
- Vials and pens are good for 28 days
Studies
- Hypoglycemic events with Lantus vs Tresiba in T1DM, JAMA (2017) [PubMed abstruse]
- Hypoglycemic events with Lantus vs Tresiba in T2DM, JAMA (2017) [PubMed abstruse]
Levemir® (insulin detemir)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
FlexTouch® Pen (100 units/ml)
- iii ml pen
- Comes in bundle of v
- FlexTouch® pen button maintains the same extension at all doses
- Compatible with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of action
- 1 - 3 hours
Duration of activity
- vi - 24 hours
- Levemir'due south duration of action depends on the dose
| Dose (units/kg) | Duration (hours) |
|---|---|
| 0.1 | 6 |
| 0.2 | 12 |
| 0.4 | 20 |
| ≥0.8 | 22 - 24 |
Elevation result
- Levemir does non accept a pronounced acme effect like NPH, but at lower doses, its elapsing of action is shorter and its waning activity tin create a summit and valley effect.
- At doses of 0.2 units/kg, it's maximum outcome occurs 3 - iv hours later dosing
- At doses of ≥ 0.4 units/kg, it'due south maximum upshot occurs 8 - 12 hours after dosing
Mixing
- DO Non MIX with other insulins
Dosing
- Dosage will vary by patient
- Levemir® may exist dosed once- or twice-daily
- In one case-daily doses should be administered with the evening repast or at bedtime
- With twice-daily dosing, the evening dose tin exist administered with the evening repast, at bedtime, or 12 hours later the morning dose
- The recommended starting dose of Levemir® in type 2 diabetics is 10 Units (or 0.1-0.2 Units/kg) given once daily in the evening or divided into a twice-daily regimen
- Levemir® is a basal insulin. See insulin dosing for more than.
- Run into converting between insulin brands and types for information on changing insulins
Other
- Levemir® should exist articulate and colorless
Storage
Unpunctured, refrigerated
- Vials and pens are proficient until expiration date on product
Unpunctured, room temp
- Vials and pens are good for 42 days
Punctured (in use)
- Vials may exist refrigerated or kept at room temperature
- Pens should be kept at room temperature (do non air-condition)
- VIals and pens are good for 42 days
Semglee® (insulin glargine)
Dosage forms
Vial (100 units/ml)
- 10 ml vial
Pen (100 units/ml)
- 3 ml pen
- Comes in package of 3 or 5 pens
- Compatible with BD® Ultra-Fine pen needles
Pharmacokinetics
Onset of action
- 1 - 3 hours
Duration of action
- 24+ hours
Mixing
- Practise Non MIX with other insulins
Dosing
- Dosage volition vary by patient
- The recommended starting dose of Semglee® in patients with type ii diabetes who are not currently treated with insulin is 0.two units/kg or up to x units one time daily
- Semglee® may be administered at any time during the mean solar day
- Semglee® should be administered at the same time every day
- Semglee® is a basal insulin. Run into insulin dosing for more.
- See converting between insulin brands and types for data on changing insulins
Other
- Semglee should be clear and colorless
- Semglee is a biosimilar to Lantus and can exist substituted for it
Storage
Unpunctured, refrigerated
- Vials and pens are practiced until expiration date on production
Unpunctured, room temp
- Vials and pens are good for 28 days
Punctured (in apply)
- Vials may be refrigerated or kept at room temperature
- Pens should exist kept at room temperature (practice non refrigerate)
- Vials and pens are good for 28 days
Toujeo® (insulin glargine)
Dosage forms
Toujeo SoloStar® Pen (300 units/ml)
- ane.5 ml pen
- Comes in package of 3 pens
- Max dose per injection is lxxx units
- Compatible with BD® Ultra-Fine pen needles
Toujeo Max® Pen (300 units/ml)
- 3 ml pen
- Comes in packet of 2 pens
- Max dose per injection is 160 units
- Compatible with BD® Ultra-Fine pen needles
Pharmacokinetics
Duration of activeness
- 24+ hours
- Steady state is reached at ≥ 5 days
Mixing
- DO Not MIX with other insulins
Dosing
- Dosage will vary by patient
- The recommended starting dose of Toujeo® in patients with type ii diabetes who are not currently treated with insulin is 0.2 units/kg once daily
- Toujeo® may be administered at whatsoever fourth dimension during the day
- Toujeo® should exist administered at the same time every mean solar day
- Toujeo® is a basal insulin. See insulin dosing for more.
- In a multidose study, the glucose-lowering result of Toujeo® was about 27% lower than that of an equivalent dose of Lantus®
- See converting between insulin brands and types for information on changing insulins
Other
- Toujeo® should exist clear and colorless
Storage
Unpunctured, refrigerated
- Pens are good until expiration date on product
Punctured (in use)
- Pens should be kept at room temperature (practise not refrigerate)
- Pens are good for 56 days
Tresiba® (insulin degludec)
Dosage forms
FlexTouch® Pen
- Comes in ii strengths:
- U-100 - 100 units/ml
- U-200 - 200 units/ml
- Pens contain 3 mls
- U-100 comes in package of 5 pens
- U-200 comes in package of 3 pens
- Uniform with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Vial (100 units/ml)
- ten ml vial
Pharmacokinetics
Onset of action
- 1 - 3 hours
Duration of action
- 24+ hours
Mixing
- DO NOT MIX with other insulins
Dosing
- Dosage volition vary by patient
- Tresiba is dosed once daily and may be given at any time during the day
- The recommended starting dose of Tresiba in insulin-naïve blazon 2 diabetics is 10 units once daily
- Tresiba is a basal insulin. See insulin dosing for more.
- Run across converting betwixt insulin brands and types for information on irresolute insulins
- Encounter Xultophy for information on Xultophy dosing
Other
- Tresiba should be clear and colorless
Storage
Unpunctured, refrigerated
- Pens and vials are proficient until expiration appointment on product
Unpunctured, room temp
- Pens and vials are good for 56 days
Punctured (in utilise)
- Pens and vials may be refrigerated or kept at room temperature
- Pens and vials are good for 56 days
Studies
- Hypoglycemic events with Lantus vs Tresiba in T1DM, JAMA (2017) [PubMed abstract]
- Hypoglycemic events with Lantus vs Tresiba in T2DM, JAMA (2017) [PubMed abstract]
- INSULIN COMBINATIONS
Humalog® Mix 75/25 | 75% insulin lispro protamine and 25% insulin lispro
Dosage forms
Vial (100 units/ml)
- 10 ml vial
KwikPen® (100 units/ml)
- iii ml pen
- Comes in package of five
- Compatible with BD® pen needles
Pharmacokinetics
Onset of activity
- ten - 30 minutes
Duration of activity
- upwardly to xx hours
Mixing
- Exercise NOT MIX with other insulins
Dosing
- Insulin lispro is a rapid-interim insulin
- Insulin lispro protamine is an intermediate-acting insulin that is formed by combining insulin lispro and protamine sulfate
- Dosage will vary by patient
- Dosage should be given within 15 minutes of a repast
- See insulin dosing for more
Other
- Humalog® Mix should be resuspended before use (see instructions with product)
- Humalog® Mix should announced uniformly cloudy with no particulate matter after resuspending
Storage
Unpunctured, refrigerated
- Vials and pens are expert until expiration engagement on product
Unpunctured, room temp
- Vials are proficient for 28 days
- Pens are good for 10 days
Punctured (in use)
- Vials may be refrigerated or kept at room temperature
- Pens should exist kept at room temperature (do not refrigerate)
- Vials are practiced for 28 days
- Pens are good for 10 days
Humalog® Mix fifty/50 | 50% insulin lispro and 50% insulin lispro protamine
Dosage forms
Vial (100 units/ml)
- 10 ml vial
KwikPen® (100 units/ml)
- 3 ml pen
- Comes in package of v
- Compatible with BD® pen needles
Pharmacokinetics
Onset of action
- x - 30 minutes
Elapsing of activeness
- upwardly to 20 hours
Mixing
- DO Not MIX with other insulins
Dosing
- Insulin lispro is a rapid-interim insulin
- Insulin lispro protamine is an intermediate-acting insulin that is formed past combining insulin lispro and protamine sulfate
- Dosage will vary by patient
- Dosage should exist given within xv minutes of a meal
- Come across insulin dosing for more
Other
- Humalog® Mix should be resuspended before use (come across instructions with product)
- Humalog® Mix should appear uniformly cloudy with no particulate matter after resuspending
Storage
Unpunctured, refrigerated
- Vials and pens are practiced until expiration date on product
Unpunctured, room temp
- Vials are skilful for 28 days
- Pens are good for 10 days
Punctured (in use)
- Vials may be refrigerated or kept at room temperature
- Pens should be kept at room temperature (do not refrigerate)
- Vials are skilful for 28 days
- Pens are good for ten days
Humulin® seventy/30 | 70% NPH and 30% regular insulin
Dosage forms
Vial (100 units/ml)
- Comes in iii ml and 10 ml vials
KwikPen® (100 units/ml)
- 3 ml pen
- Comes in package of 5
- Compatible with BD® pen needles
Pharmacokinetics
Onset of activeness
- 30 - 60 minutes
Duration of action
- up to 20 hours
Mixing
- Practice Non MIX with other insulins
Dosing
- Regular insulin is a short-interim insulin
- NPH is a intermediate-acting insulin
- Doses should exist given 30 - 45 minutes before a meal
- See dosing 70/30 insulin and NPH dosing for more
Other
- Humulin® 70/30 should be resuspended before use (come across instructions with product)
- Humulin® 70/thirty should announced uniformly cloudy with no particulate matter after resuspending
Storage
Unpunctured, refrigerated
- Vials and pens are proficient until expiration date on product
Unpunctured, room temp
- Vials are good for 31 days
- Pens are good for 10 days
Punctured (in use)
- Vials may be refrigerated or kept at room temperature
- Pens should be kept at room temperature (practise non refrigerate)
- Vials are good for 31 days
- Pens are good for 10 days
Novolin® 70/thirty | 70% NPH and 30% regular insulin
Dosage forms
Vial (100 units/ml)
- 10 ml vial
FlexPen (100 units/ml)
- 3 ml pen
- Comes in carton with 5 pens
- Uniform with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of action
- 30 - hour
Duration of action
- up to 20 hours
Mixing
- Practice NOT MIX with other insulins
Dosing
- Regular insulin is a curt-interim insulin
- NPH is a intermediate-interim insulin
- Doses should be given 30 - 45 minutes earlier a meal
- See dosing 70/thirty insulin and NPH dosing for more than
Other
- Novolin® 70/30 should be resuspended earlier use (see instructions with product)
- Novolin® 70/30 should appear uniformly cloudy with no particulate matter after resuspending
Storage
Unpunctured, refrigerated
- Vial and pens are good until expiration date on product
Unpunctured, room temp
- Vials are skilful for 42 days
- Pens are good for 28 days
Punctured (in use)
- Vials and pens should be kept at room temperature (exercise not refrigerate)
- Vials are practiced for 42 days
- Pens are good for 28 days
Novolog® Mix seventy/30 | 70% insulin aspart protamine and 30% insulin aspart
Dosage forms
Vial (100 units/ml)
- 10 ml vial
FlexPen® (100 units/ml)
- 3 ml pen
- Comes in packet of 5
- Compatible with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of action
- 10 - thirty minutes
Duration of activeness
- upwards to 20 hours
Mixing
- Exercise NOT MIX with other insulins
Dosing
- Insulin aspart is a rapid-acting insulin
- Insulin aspart protamine is an intermediate-interim insulin that is formed past combining insulin aspart and protamine sulfate
- Dosage volition vary by patient
- Doses should exist given within fifteen minutes of a meal
- See insulin dosing for more
Other
- Novolog® Mix should be resuspended before apply (run into instructions with product)
- Novolog® Mix should appear uniformly cloudy with no particulate thing after resuspending
Storage
Unpunctured, refrigerated
- Vials and pens are proficient until expiration date on product
Unpunctured, room temp
- Vials are expert for 28 days
- Pens are practiced for 14 days
Punctured (in apply)
- Vials may exist refrigerated or kept at room temperature
- Pens should be kept at room temperature (do not refrigerate)
- Vials are good for 28 days
- Pens are good for 14 days
Ryzodeg® lxx/30 | seventy% insulin degludec and 30% insulin aspart
Dosage forms
FlexTouch® Pen (100 units/ml)
- Pens contain 3 ml
- Comes in package of v pens
- Compatible with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Onset of action
- ten - 30 minutes
Elapsing of activity
- 24+ hours
Peak effect
- 1/two - 2 hours
Mixing
- DO NOT MIX with other insulins
Dosing
- Insulin aspart is a rapid-acting insulin
- Insulin degludec is a long-acting insulin
- Dosage will vary past patient
- May be given in one case or twice daily with any main meal
- A rapid- or short-acting insulin may be given at other meals if needed
- Doses should be given within xv minutes of a meal
- See insulin dosing for more than
Other
- Ryzodeg should exist clear and colorless
Storage
Unpunctured, refrigerated
- Pens are skillful until expiration date on product
Unpunctured, room temp
- Pens are proficient for 28 days
Punctured (in use)
- Pens should exist kept at room temperature (do not refrigerate)
- Pens are proficient for 28 days
- INSULIN + GLP-ane ANALOG
Soliqua® (insulin glargine + lixisenatide)
Dosage forms
Pen (100/33)
- 100 units/ml insulin glargine and 33 mcg/ml lixisenatide
- Pens comprise 3 ml
- Comes in bundle of 5 pens
- Pen window shows units of insulin glargine
Pharmacokinetics
Parameters are for insulin glargine merely
Onset of action
- 1 - 3 hours
Elapsing of activity
- 24+ hours
Mixing
- DO NOT MIX with other insulins
Dosing
- Insulin glargine is a long-acting insulin
- Lixisenatide is a GLP-1 analog
- Pen is dialed to units of insulin glargine. Minimum dose pen tin deliver is 15 units and max is 60 units.
- If inadequate command on < thirty units of basal insulin or lixisenatide, starting dose is 15 units once daily
- If inadequate command on 30 - 60 units of basal insulin, starting dose is 30 units once daily
- Titrate dose up or down by 2 - 4 units every week based on claret sugar goals
- Max dose is 60 units
- Administrate in one case a twenty-four hour period within the hour prior to the offset repast of the day
- Meet insulin dosing for more than
Other
- Soliqua should be clear and colorless to almost colorless
Storage
Unopened / Unused pens
- Store in refrigerator
- Skillful until expiration appointment on product
Later first utilise
- Pens should be kept at room temperature (practice non refrigerate)
- Pens are good for 28 days
Xultophy® (insulin degludec + liraglutide)
Dosage forms
Pen (100/iii.6)
- 100 units/ml insulin degludec and 3.vi mg/ml liraglutide
- Pens incorporate 3 ml
- Comes in bundle of 5 pens
- Pen window shows units of insulin degludec
- Compatible with NovoFine, Novofine Plus, NovoTwist, and BD pen needles
Pharmacokinetics
Parameters are for insulin degludec only
Onset of activeness
- 1 - 3 hours
Elapsing of action
- 24+ hours
Mixing
- DO NOT MIX with other insulins
Dosing
- Insulin degludec is a long-acting insulin
- Liraglutide is a GLP-one analog
- Pen is dialed to units of insulin degludec. Minimum dose pen can deliver is ten units and max is 50 units.
- Recommended starting dose is sixteen units once daily
- Titrate dose upwards or downwardly past 2 units every 3 - 4 days based on claret saccharide goals
- Max dose is 50 units
- Administer at the same time each mean solar day with or without food
- Patients who persistently require less than 16 units should discontinue Xultophy and use another production
- See insulin dosing for more
Other
- Xultophy should be clear and colorless
Storage
Unopened / Unused pens
- Store in refrigerator
- Good until expiration date on product
After get-go utilize
- Shop at room temperature or in a refrigerator
- Practiced for 21 days
- INSULIN COST AND ASSISTANCE
| Insulin | Reduced cost programs | Free programs |
|---|---|---|
| Basaglar, Humalog, Humulin Due north, Humulin R, Humalog Mix 50/l, Humalog Mix 75/25 | Lilly Insulin Value Plan
| Lilly Cares program
|
| Lantus, Toujeo, Admelog, Apidra | Sanofi Insulin Value Savings Program
| Sanofi Patient Connection
|
| Levemir, Tresiba, Novolog, Fiasp Novolin N, Novolin R, Novolin 70/30, Novolog Mix 70/30 | My$99Insulin Program
Walmart (Novolin N, Novolin R, Novolin seventy/thirty, Novolog)
| NovoCare Patient Assistance Program
|
- OVER-THE-COUNTER INSULIN
- In many U.S. states, insulin can be bought over-the-counter (without a prescription) at pharmacies
- Over-the-counter insulin is typically express to Regular, NPH, and the seventy/30 mixes of NPH and regular
- The availability of over-the-counter insulin is intended to help diabetics in a bind or emergency
- A simple way to find out if a land allows over-the-counter insulin is to telephone call a chemist's shop in that country
- BIBLIOGRAPHY
- Manufacturer's bundle insert
Source: https://www.straighthealthcare.com/insulin-chart.html
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